What is NAD+?
Nicotinamide Adenine Dinucleotide or NAD+ is an essential coenzyme that is present in virtually every cell in the human body. NAD+ is directly involved in a myriad of metabolic processes in the body, including ATP production, DNA repair, immunological functions, mitochondrial health, modulated gene expression, and cellular energy. It is present not only in mammalian cells but can also be found in plants, yeast, and bacteria.
NAD+ was first discovered by Sir Arthur Harden and William Young John when the duo were working to understand the concept of fermentation in 1906. However, it took another two decades before Harden, in conjunction with Hans von Euler-Chelpin, made another significant stride in NAD+ recognition. They both shared the Nobel Prize in 1929, owing to their laudable research on fermentation. Euler-Chelpin eventually revealed that two nucleotides form the NAD+ structure, and they are the fundamental basis for the nucleic acid that form DNA. Further studies by Nobel Prize-winning scientist Arthur Kornberg in the next decade, and award-winning scientists like Jack Preiss and Phillip Handler – who described the nicotinic acid pathway – helped shed more scientific insight into the importance of NAD+.
How Does NAD+ Work?
Without having to go knee-deep into the science of it, NAD+ works by shuffling electrons around your enzymes. An oxidized form of NAD+ joins with an electron from one molecule. The moment it partners with another molecule, it becomes NADH (Nicotinamide Adenine Dinucleotide + Hydrogen), and every time it shares that electron with a different molecule, it returns to its original NAD+ state.
This continuous exchange of electrons helps to power your enzymes, and those enzymes help generate a series of chemical reactions that keep your cell and body working like a well-oiled machine. To succinctly put, our bodies would shut down without it.
What Does NAD+ Do?
For starters, it helps to convert nutrients into energy in the form of ATP for cells. Additionally, it ensures that proteins are harnessed in their correct form to perform a variety of functions in the human body, including Mitochondrial function, gene expression, calcium signaling, DNA repair, maintaining chromosomal integrity, and epigenetic modification.
NAD+ has also been shown to have significant effects on cognition, aging, energy levels, and digestion. The coenzyme is also linked to the increase in the production of serotonin – a neurotransmitter in the body associated with mood regulation and may help alleviate the symptoms of anxiety and depression.
Additionally, it is said to be immensely beneficial to people undergoing recovery and detox for substance abuse. The treatment has been shown to help with withdrawal symptoms, limit cravings, and boost energy levels.
However, studies have shown that your body does not produce an infinite amount of NAD+ and that your body makes less of it as you age.
How You Can Get More NAD+
The most efficient and sustainable method of receiving NAD+ is through an NAD+ IV Therapy. There are currently no oral supplements that can directly provide NAD+. Besides, absorbing it via the gastrointestinal tract is extremely difficult. However, there is ongoing research exploring the possibility.
Nevertheless, your body can be prompted to produce NAD+ if supplements known as precursors to NAD+ are taken. These include nicotinamide riboside, niagen, and nicotinic acid. Your body can absorb and ultimately convert any of those supplements to NAD+.
However, there are certain side effects associated with the excessive consumption of these supplements. Presently, the most efficient and safest method of getting more NAD+ is via IV Therapy
What Are the Benefits of NAD+?
The energy expended by your body to maintain normal bodily function is referred to as metabolism. Naturally, as we age, our metabolism diminishes. This can trigger weight gain and cause exhaustion. Scientific Studies have shown that NAD+ plays a pivotal role in ensuring a normal metabolic function of the body. This can help to boost your body’s overall vitality and energy level.
Additionally, it ensures that proteins are in the right form to fuel the body. For instance, insulin receptor proteins that are wrongly formed can halt the signal telling it to receive the energy present in your bloodstream, as shown in this study.
It is also crucial to the body’s redox reactions (oxidation-reduction). These chemical reactions are part of a chain of complex processes where the body converts food into energy that is used to fuel your cells.
Enhanced Neurological Health
Aging often accompanies a decrease in neurologic and cognitive health. Some of these conditions include foggy memory, dementia, and mental fatigue.
By boosting the production of Sirtuin (SIRT), NAD+ helps to protect the brain from age- associated mental conditions. Recent research has shown that the coenzyme helps to restore and rejuvenate the brain by significantly limiting the effects of neurodegenerative illnesses and loss of cognitive function.
NAD+ IV Therapies are strongly linked to improved mental clarity and neurological health, including better memory and enhanced focus.
Anti-Aging and Muscle Protection
Dr. David Sinclair, a professor of genetics at Harvard Medical School, has spent several years studying the connection between NAD+ and vascular aging. As we grow older, our arteries begin to die slowly. Vascular aging describes a situation where our tiniest blood vessels wither and dies – as we age – and consequently reduces the flow of blood to our tissues and organs. Using NAD+, This research has been able to
successfully reverse the effect of vascular aging and its impact on muscular health. According to Dr. Sinclair, SIRT1 and NAD+ are both vital to the normal functioning of blood vessels and muscles. Unfortunately, they both decline in function as we age. Also, our muscles need a good supply of blood to work properly. At the same time, exercise may help limit the onset of vascular aging, although it is often not enough.
Addiction and Recovery
NAD+ IV therapy is lauded as a natural approach for people undergoing addiction and recovery treatment. Rather than trying to combat withdrawal symptoms with medication – which often has several side effects – NAD+ is touted as a more holistic solution.
Substance abuse rewires the way chemical receptors work in the brain. This is in addition to depleting essential nutrients and vitamins in the body. NAD+ is often referred to as the ‘crown jewel of detox’ for people undergoing addiction treatment. It does this by binding to opiate receptors in the brain. Studies have shown that it can help reduce cravings for the substance and ultimately reduces the chance of a relapse.
NAD + IV therapy works at the body’s molecular level and helps with the restoration of proper biochemistry that helps _________ (fill in the blank). Yes, there is a good bit of anecdotal evidence and as we showcased in this article on NAD+, there is also a good bit of scientific data that demonstrates evidence of tangible results. Results with real people who are daily living examples of the benefits of NAD+ IV therapy.
When it comes to a quick immune boost or preparing for a race, IV therapy serves an immediate benefit . NAD+ IV therapy produces best results when a treatment plan is organized and determined by your HydraMed IV Specialist and you. This may be done in person or over the phone via text or a call at 720-477-6302.