What Does the Science Say About NAD+ Supplementation? - HydraMed Mobile IV Therapy >

What Does the Science Say About NAD+ Supplementation?

Nicotinamide Adenine Dinucleotide (NAD+) is critical for several physical benefits, including cellular function. This essential micronutrient is present across millions of cells inside the body. It plays a crucial role in catalyzing multiple chemical reactions to repair, build up, and defend various molecules that constitute our body makeup. Summed up, these multiple benefits significantly delay the body’s aging process, thereby also making NAD+ a potent anti-aging resource.

Even though NAD+ is crucial for cellular health, it is not always available in sufficient amounts. As we age, the body loses significant portions of its NAD+ reserves. Also, besides aging, there are other factors that can contribute to its rapid depletion.

Fortunately, however, the body’s cells are equipped with several mechanisms to develop more NAD+. One of such ways is by using the smaller building blocks available in NAD+-rich diets or through supplementation, which offers more rapid benefits.

NAD+ depletion is mainly linked to aging, psychological stress, and a wide range of several other factors, including certain diseases. When the body becomes deficient in NAD+, our cellular defense becomes weaker, making it easier for harmful diseases to penetrate and cause harm.

What is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme, present in all living cells, and essential for the central role it plays in facilitating various metabolic processes in the body. NAD+ can exist in two distinct forms, NAD+ (Oxidized form) and NADH (Reduced form — The H represents Hydrogen).

Nicotinamide Adenine Dinucleotide functions as a crucial component for several metabolic processes. During metabolism, NAD+ contributes to redox reactions by conveying electrons from one reaction to another. It also plays an essential role in regulating pivotal cellular processes and energy production. However, the body’s NAD+ levels are known to decline with age.

NAD+’s direct links with metabolism reactions provide the body with two pivotal benefits. The first is facilitating the conversion of bodily nutrients into energy. The second is by taking the role of a helper molecule to assist specific proteins in regulating other crucial cellular functions. These benefits are incredibly essential to the body’s overall well-being. When combined, it also helps to significantly delay aging symptoms and prevent the onset of various diseases.

What are The Signs of NAD+ Deficiency?

Several factors can influence the rapid depletion of NAD+ in the body. The most common causes include aging and the onset of certain diseases. If NAD+ becomes deficient, the body can give a range of signs and signals to notify us to replenish the lost nutrient. These signs may include:

  • Irregular fatigue
  • Premature aging signs (wrinkling, skin deterioration, fine lines, etc.)

Severe cases of NAD+ deficiencies may cause or significantly contribute to the emergence of such diseases as:

  • Diabetes
  • Myocardial Ischemia
  • Cerebral Ischemia

 NAD+ IV TherapyWhy is NAD+ Supplementation Important?

NAD+ offers many nutritional and therapeutic benefits to the body. It is effective for preventing the onset of various diseases and senescence. NAD+ achieves most of its beneficial effects using multiple strategies, including:

  • Weakening Mitochondrial Alterations
  • Blocking Pathological Pathways
  • Repairing/Reversing the Effects of DNA Damage & Oxidative Stress
  • Optimizing the Activities of Important Enzymes (such as Sirtuins, AP Endonuclease, and Glyceraldehyde-3-Phosphate Dehydrogenase)

When the body runs short on its NAD+ reserves, the cells become weaker and more vulnerable to various disease agents and other risk factors. This makes it easy to acquire certain life-threatening diseases.

Potential Health Benefits of Supplementing NAD+ Through NAD+ IV Therapy

NAD+ coenzymes are utilized for multiple complex processes in the body. This is because they offer several bodily advantages that benefit our overall health and well-being. Here’s a concise breakdown of different ways in which the body benefits from NAD+.

Pain Relief

Being active members of a protein molecule family (that are notable influencers of the body’s antioxidant expression and inflammatory response), Sirtuins can contribute significantly to pain relief. For instance, some Sirtuins help reduce inflammation, thereby causing quicker relief from pain. NAD+ coenzymes facilitate the optimal development and functioning of Sirtuins. As such, patients can benefit from boosting their NAD+ levels through IV therapy.

Optimize Cognitive Function

Besides their pain relief and anti-inflammatory benefits, Sirtuins also help to improve our body’s cell resistance to stress and cognitive decline. Studies reveal that higher levels of NAD+ can help to boost patients’ cell resistance, thereby potentially improving cognitive function by:

  • Boosting memory
  • Facilitating brain regeneration
  • Improving concentration
  • Improving mental clarity
  • Improving mood
  • Increasing neurological function
  • Increasing one’s ability to focus
  • Reducing symptoms of depression

Energy Boost

NAD+ works with ATP (Adenosine Triphosphate) to provide the body with several essential benefits. ATP is a vital contributor to cell energy. It is commonly referred to as the cell powerhouse because it helps fuel several critical cellular activities, such as muscle contractions, cellular respiration, and DNA replication.

NAD+ IV therapy helps to significantly increase the body’s production of ATP. Consequently, this helps boost overall energy levels and reduce feelings of exhaustion and tiredness. NAD+ IV is often incorporated in the treatment of patients with chronic fatigue syndrome (CFS) and for patients recovering from jetlag.

Athletic Performance Boost

Because of the essential roles that NAD+ plays in boosting the body’s energy levels and cognitive function, it can benefit physical and athletic performance immensely. This is true because one’s reaction times and overall performance are significantly influenced by energy levels and the ability to think clearly.

Furthermore, studies reveal that NAD+ also plays a pivotal role in muscle development. It achieves this by standing in as a ready fuel reserve to refire muscle tissues during strenuous activities and as a repairer afterward.

Weight Loss and Weight Management

One of the primary functions of NAD+ is its significant contributions in facilitating various metabolic processes. When administered in conjunction with regular exercise and a proper healthy diet, NAD+ can offer significant weight loss benefits. This weight management technique can be highly effective for older patients who have started to experience slower metabolism associated with aging.


Sirtuins play several vital roles to positively impact cognitive function, pain management & relief, and inflammation. Notably, they are also highly dependent on NAD+ to function correctly.

One particular Sirtuin, known as Sir2p, offers several notable benefits that help to significantly suppress or slow down the body’s aging process while boosting overall health spans. By significantly impacting the development and optimal function of Sirtuins, NAD+ also drastically affects the effectiveness of Sir2p Sirtuins. As such, with the proper administration of NAD+, patients can begin to see improvements in the appearance of fine lines, wrinkles, and a variety of other symptoms associated with aging.

NAD+ IV Therapy

Prevention of the Onset of Certain Diseases

Lower levels of NAD+ have been linked with several metabolic and cardiovascular diseases, such as fatty liver disease, diabetes, and several other adverse health conditions. As such, we are supplementing with higher doses of NAD+ can be beneficial in treating patients with such situations. However, more studies are ongoing to clearly define the relationship between lower levels of this vital coenzyme and several metabolic and cardiovascular diseases.

Addiction Recovery

Addiction problems are usually a result of complex psychological disorders that influence how specific signals are conveyed to and from the brain. Research by the National Institute on Drug Abuse reveals that 40% to 60% of people struggling with an addiction relapse.

Although alcohol recovery and cessation can be challenging, NAD+ offers highly-effective benefits that help hasten the process by minimizing withdrawal symptoms. It achieves this by making the withdrawal process more tolerable for patients, without the risk of acute side effects in the future.

It also works well in conjunction with psychotherapy or counseling. NAD+ is often incorporated in the treatment of patients trying to detoxify or recover from alcohol, prescription drugs dependencies, opioid, and the effects of specific chemical intolerances.

NAD+ IV TherapyHow to Benefit from an NAD+ Supplement

Supplementing with NAD+ can be highly beneficial because of the numerous health advantages. Notwithstanding, wrongful administration can bring potential adverse effects. That said, there are a number of ways through which one can supplement a deficiency in NAD+. The options range from oral to sublingual and IV therapy. However, the first step is to speak with your doctor and go for a test to ascertain the cause of the symptoms. You can contact professional IV Therapy providers like HydraMed.

IV Therapy is the safest and fastest means to benefit from an NAD+ supplement. Unlike other methods, it is administered directly to the veins and bloodstream. This way, it completely bypasses any direct interactions with the intestinal tract and digestive system and any other unnecessary metabolic processes. This way, 100% of the administered supplement successfully remains in the body, offering maximum results over shorter treatment intervals.

If you experience any unpleasant symptoms related to a deficiency in NAD+, you can benefit from NAD+ IV Therapy. It would be best to get tested and seek professional counsel from a certified IV Therapy provider. Also, consult with your doctor to know whether or not you are allergic to NAD+ supplements and if other factors will permit. This way, you can benefit from a wide range of Pepcid (Famotidine) solutions, such as:

  • NAD+ IV Therapy: Provides vast support and benefits like improved health, auto-immune disease, anti-aging, and more to help you look and feel your best.
  • Anti-Aging IV Therapy: Accelerates various regeneration processes to protect cells and ultimately help decrease the onset of cellular aging.


NAD+ provides the body with numerous benefits, including metabolic and cellular health benefits. Although this vital coenzyme is essential for the body’s overall well-being, it depletes significantly as we age due to several other factors, including certain adverse medical or health conditions.

It is vital to supplement the body’s NAD+ levels, especially if it is deficient, to enhance optimal cellular function and overall well-being. One effective way to achieve this is through a mobile IV Therapy provider. This way, you can benefit extensively from NAD+ without risking unwanted future side effects and such. Ensure also to speak with a qualified medical representative and avoid self-medicating. Stay safe.